產(chǎn)品詳情
簡單介紹：
Anti-Phospho-beta-Arrestin 1 (Ser412)抗體產(chǎn)品質(zhì)量穩(wěn)定，實驗效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-Phospho-beta-Arrestin 1 (Ser412)抗體用于**組化實驗,WB實驗,相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-Phospho-beta-Arrestin 1 (Ser412)
Cat. Number:
Anti-Phospho-beta-Arrestin 1 (Ser412)抗體XY-3048R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Beta Arrestin 1 is a member of a family of proteins that are widely expressed but especially abundant in the central nervous Anti-Phospho-beta-Arrestin 1 (Ser412)抗體system. Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling. It mediates agonist dependent desensitization and internalization of G protein coupled receptors (GPCRs, e.g., beta 2 adrenergic receptor). After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs are phosphorylated by G protein receptor kinases (GRKs) on serine residues. Beta Arrestin 1 has important roles in the cytoplasm and at the plasma membrane in the desensitization and internalization of G protein coupled receptors (GPCRs) and is increasingly appreciated to play an important role in the endocytosis and signaling of GPCRs. Beta Arrestin 1 in the cytosol is phosphorylated by ERK1 and 2 on serine 412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane. Serine 412 is then dephosphorylated and the GPCRs are internalized, leading to activation of the Ras, Raf, ERK1 and 2 signaling pathway.
Also known as:
Anti-Phospho-beta-Arrestin 1 (Ser412)抗體beta Arrestin 1 (phospho S412); p-beta Arrestin 1 (phospho S412); ARB 1; ARB1; ARR 1; ARR1; ARRB 1; ARRB1; Arrestin beta 1.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Cow, .
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human beta-Arrestin 1 around the phosphorylation site of Ser412.
●
Predicted Molecular Weight: 45kDa.
Storage:
Shipped at 4℃, Anti-Phospho-beta-Arrestin 1 (Ser412)抗體Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal workingAnti-Phospho-beta-Arrestin 1 (Ser412)抗體 dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal workingAnti-Phospho-beta-Arrestin 1 (Ser412)抗體 dilutions must be determined by the end user.
xy-12360R Epiphycan硫酸軟骨素蛋白多糖3抗體
xy-10151R Exportin 1/CRM1染色體區(qū)域穩(wěn)定蛋白/核輸出蛋白1抗體
xy-10154R Phospho-ELk1(Ser383)磷酸化細(xì)胞轉(zhuǎn)錄因子ELK1抗體
xy-12341R ETV2ETS相關(guān)蛋白71抗體
xy-12347R EDA外胚層發(fā)育**蛋白1抗體
xy-13114R ETV3LETV3L蛋白抗體
xy-2571R EphB6酪氨酸蛋白激酶受體B6抗體
xy-2880R LPA1溶血磷脂酸受體蛋白1抗體
xy-2881R LPA2溶血磷脂酸受體蛋白2抗體
xy-2882R LPA3溶血磷脂酸受體蛋白3抗體
xy-2883R EDG6內(nèi)皮細(xì)胞的分化蛋白6抗體
xy-6005R EXTL2外生性骨疣樣蛋白2抗體
xy-5334R phospho-EIF4EBP1 (Ser100)磷酸化eIF4E結(jié)合蛋白抗體
xy-5337R phospho-EIF4EBP1(Ser111)磷酸化eIF4E結(jié)合蛋白抗體
xy-3615R ESM1內(nèi)皮細(xì)胞特異性分子1抗體
xy-3841R eIF3F真核翻譯起始因子3F抗體
xy-3842R eIF3H真核翻譯起始因子3H抗體
xy-3843R eIF4G真核翻譯起始因子4G抗體
xy-3844R eIF6β4整合素結(jié)合蛋白抗體
xy-9807R ECRG4食道癌相關(guān)基因4蛋白抗體
xy-2343R EPO紅細(xì)胞生成素抗體
xy-3880R EPHX2胞漿環(huán)氧化物水解酶抗體
xy-6213R Estrogen Related Receptor gamma雌**受體相關(guān)蛋白3抗體
xy-6212R Estrogen Related Receptor beta雌**相關(guān)受體β抗體
xy-6264R EMP2上皮細(xì)胞膜蛋白2抗體
xy-2947R ERG25甲基固醇羥化酶單加氧酶1抗體
xy-6527R EST1A端粒酶結(jié)合蛋白EST1A抗體
xy-6528R EZH1組蛋白賴氨酸N-甲基EZH1抗體
xy-6532R Epithelial Stromal Interaction 1上皮間質(zhì)相互作用蛋白1抗體
xy-6533R EIG121雌**誘導(dǎo)基因121蛋白抗體
xy-5884R Endomucin內(nèi)皮粘蛋白EMCN抗體
xy-5883R EBP50細(xì)胞骨架連接質(zhì)膜蛋白抗體
xy-5807R ELMO1吞噬細(xì)胞運(yùn)動蛋白1抗體
